The AmoyDx® NGS Data Analysis System (ANDAS) consists of a local workstation and a pre-installed, CE/IVD classified NGS analysis software. The workstation is based on a Dell PowerEdge server, which can either be directly connected to an Illumina sequencer or integrated into an existing local network. Data analysis with the ANDAS analysis software is performed via a user-friendly, browser-based interface. The software contains specific modules for the analysis of the various AmoyDx® NGS panels, in which several databases for designating and evaluating variants are integrated. An internet connection of the server is not necessary, as the databases are updated by regular upgrades of the modules. This means that your sequence data can be analyzed quickly, easily and reliably. The results can be exported in the form of an Excel list which, in addition to the quality parameters of the sequencing data, also contains the classification of variants and links to the corresponding sequence databases (e.g. COSMIC, ClinVar). The BAM/BAI- and VCF-files can also be exported into IGV for the evaluation of individual variants.
CE/IVD classified
From raw data to tumor genetic analysis in just a few steps
Display of important quality parameters such as Q30, sequencing depth or coverage of target regions for each sample
Display of variant classification from various databases, e. g. ClinVar, COSMIC and BRCA Exchange
Regular updates of the databases used
Local workstation as a secure stand-alone solution for data processing
Computer type | Dell OEM Ready PowerEdge Server |
Operating system | Linux (CentOS) |
RAM | 4 x 32 GB RDIMM |
Hard disk configuration | 8 x 8 TB Hot-plug Hard Drive* |
Available storage space | 24 TB* |
External interfaces | 2 x Ethernet: LAN Gb1 (DHCP server); LAN Gb2 (DHCP client/static) |
Dimensions (W x D x H) | 200 x 680 x 459 mm |
Power supply | 230 V, 50 Hz; Dual Hot-plug Redundant Power Supply, 1100 W |
* Subject to change
Software
ANDAS analysis software with modules for different kits, display of quality parameters for sequencing and analysis results, module-specific data export in various formats such as BAM/BAI, VCF and Excel file possible.
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